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Results for "

Betulinic acid

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

6

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10529
    Betulinic acid
    Maximum Cited Publications
    22 Publications Verification

    Lupatic acid; Betulic acid

    		 Apoptosis Topoisomerase HIV Autophagy Mitophagy NF-κB Endogenous Metabolite Parasite Infection Inflammation/Immunology Cancer
    Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties .
    <em>Betulinic</em> acid
  • HY-N0084
    Betulinaldehyde
    4 Publications Verification

    Betulinic aldehyde; Betunal

    		 Bacterial Infection Cancer
    Betulinaldehyde (Betunal) Has anti-cancer and anti-staphylococcus aureus activity. Betulinaldehyde Suppressible Akt, MAPK sum STAT3 Signal path, increase self-transfer, Suppression A549 Cellular vitality, increase and transfer. Betulinaldehyde suppresses PLCγ1/Ca 2+/MMP9 signal pathway, has a key effect on vascular plasticity, and is available for cardiovascular disease (CVD) research.
    Betulinaldehyde
  • HY-N3558
    Ceanothic acid

    Emmolic acid

    		 Others Cancer
    Ceanothic acid (Emmolic acid) is a ring-A homologue of betulinic acid. Ceanothic acid inhibits OVCAR-3, HeLa, and FS-5 cells with the cell survival of 68%, 65%, and 81%, respectively .
    Ceanothic acid
  • HY-N6587
    Betulinic acid methyl ester

    Methyl betulinate

    		 Parasite Others
    Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity .
    <em>Betulinic</em> acid methyl ester
  • HY-115720
    Betulinic acid derivative-1

    		Others Inflammation/Immunology
    Betulinic acid derivative-1 exhibits distinguished activities on inhibiting osteoclast (OC) differentiation with an IC50 value of 1.86 μM.
    <em>Betulinic</em> acid derivative-1
  • HY-N0842
    Bevirimat
    1 Publications Verification

    PA-457; MPC-4326; YK FH312

    		 HIV Infection
    Bevirimat (PA-457; MPC-4326; YK FH312) is an anti-HIV agent derived from a betulinic acid-like compound; is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition.
    Bevirimat
  • HY-N3361
    (3β,4α)-Lup-20(29)-ene-3,23-diol

    		Others Cancer
    (3β,4α)-Lup-20(29)-ene-3,23-diol (compound 11) is a natural lupane-type triterpenes betulinic acid with anti-tumor activity .
    (3β,4α)-Lup-20(29)-ene-3,23-diol
  • HY-146338
    RPR103611

    		HIV Infection
    RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC50s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively .
    RPR103611
  • HY-101597
    NVX-207

    		Apoptosis Cancer
    NVX-207, a Betulinic acid-derived anti-cancer compound, shows anti-tumor activity (mean IC50=3.5 μM) against various human and canine cell lines. NVX-207-induced apoptosis is associated with activation of the intrinsic apoptotic pathway via cleavage of caspases -9, -3, -7 and of PARP .
    NVX-207
  • HY-155542
    RORγ antagonist 1

    		ROR Cancer
    RORγ antagonist 1 (compound 22), a potent betulinic acid derivative, is an antagonist of RORγ (KD=0.18 μM). RORγ antagonist 1 exhibits anti-proliferative activity in HPAF-II pancreatic cancer xenograft model. RORγ antagonist 1 inhibits RAS/MAPK and AKT/mTORC1 pathway, and induces caspase-dependent apoptosis in pancreatic cancer cells .
    RORγ antagonist 1

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